RISC-V has been adopted with a record-breaking speed in pretty much all applications from general-purpose tiny MCUs to datacenter AI/ML accelerator SoCs. In this keynote, we will give examples of RISC-V applications and solutions to support them; in particular, we will also analyze various approaches for matrix multiplication extension to embrace AI/ML acceleration directly in RISC-V architecture. In addition, ISO 26262 certified automotive electronics solutions have been highly sought after in recent years due to multiple catalysts. In the second part of the keynote, we will talk about how RISC-V solutions address such market, some successful examples, and new technical challenges we should look into.