Abstract: Simpira Permutation is a Permutation design using the AES algorithm. The AES algorithm is the most widely used in the world, and Intel has developed a hardware accelerated AES instruction set (AES-NI) to improve the performance of encryption. By using AES-NI, Simpira can be improved further. However, low-end processors that do not support AES-NI require efficient implementation of Simpira optimization. In this paper, we introduce a optimized implementation of a Simpira Permutation in 8-bit AVR microcontrollers and 32-bit RISC-V processors, that do not support the AES instruction set. We firstly pre-computed round keys and omitted the Addroundkey. Afterward, the MixColumn and InvMixColumn of the final round (i.e. 12-th), which were added unnecessarily due to characteristics of Simpira using AES-NI, were omitted. In the AVR microcontroller, the Addroundkey consists of 16 operations, but it has been optimized by eliminating operations where the value of roundkeys is \texttt{0x00}, omitting Addroundkey to 4 operations. In the RISC-V processor, it is implemented using a same optimization technique of AVR implementation. We have carried out experiments 8-bit ATmega128 microcontroller and 32-bit RISC-V processor, which shows up-to \texttt{5.76× and 37.01×} better performance enhancement than reference codes for the Simpira Permutation, respectively.